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Journal: bioRxiv
Article Title: Hyaluronic Acid-Alginate Hydrazone Crosslinked Hydrogels Support the Generation and Maturation of V2a Interneurons
doi: 10.64898/2026.06.01.729352
Figure Lengend Snippet: Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked hyaluronic acid-alginate (HA-Alg) hydrogels.
Article Snippet: HA-TBA was made by dissolving
Techniques: Polymer