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Lifecore Biomedical sodium hyaluronate
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Lifecore Biomedical sodium hyaluronic acid
Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked <t>hyaluronic</t> acid-alginate (HA-Alg) hydrogels.
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Altergon Italia Srl sodium hyaluronate
Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked <t>hyaluronic</t> acid-alginate (HA-Alg) hydrogels.
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Valeant Pharmaceuticals sodium hyaluronate
Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked <t>hyaluronic</t> acid-alginate (HA-Alg) hydrogels.
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sodium hyaluronate - by Bioz Stars, 2026-10
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Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked hyaluronic acid-alginate (HA-Alg) hydrogels.

Journal: bioRxiv

Article Title: Hyaluronic Acid-Alginate Hydrazone Crosslinked Hydrogels Support the Generation and Maturation of V2a Interneurons

doi: 10.64898/2026.06.01.729352

Figure Lengend Snippet: Alginate was oxidized to reveal aldehyde groups for crosslinking (Alg-OX). An EDC/HoBt coupling reaction was performed with HA-Nor to form HA functionalized with adipic acid dihydrazide and norbornene (HA-Nor-ADH). A photoinitiated reaction between HA-Nor-ADH and the terminal cysteine on the IKVAV or RGD peptide was then performed with UV light at a wavelength of 365 nm. The terminal products of these reactions, HA-Nor-ADH and Alg-Ox, were mixed at different polymer concentrations to produce hydrazone crosslinked hyaluronic acid-alginate (HA-Alg) hydrogels.

Article Snippet: HA-TBA was made by dissolving sodium hyaluronic acid (Lifecore Biomedical LLC, Chaska, MN) (1 g, 2.64 mmol) for 20 minutes in 20 mL of double distilled water (ddH 2 O) at 2% w/v.

Techniques: Polymer